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Research Detail

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Mohammad Fahim Kadir
Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh

Muhammad Shahdaat Bin Sayeed
Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh

Nurul Islam Setu
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh

Asif Mostafa
Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, Bangladesh

M.M.K. Mia
Former Principal Scientific Officer and Consultant, Bangladesh National Herbarium, Bangladesh

Ethnopharmacological relevance: There is very limited information regarding plants used by traditional healers in Bandarban Hill Tracts (BHT), Bangladesh for treating general as well as complex ailments. Current study provides significant ethnopharmacological information, both qualitative and quantitative on medical plants in BHT. Aim of the study This study aimed to collect, analyze and evaluate the rich ethnopharmacologic knowledge on medicinal plants in Thanchi, BHT and attempted to identify the important species used in traditional medicine. Further analysis was done by comparison of the traditional medicinal use of the plants with the available scientific literature data. Materials and methods: The field survey was carried out in a period of several years in Thanchi upazilla of Bandarban districts, Bangladesh. A total of 53 Traditional Health Practitioners (THPs) were interviewed through open-ended and semi structured questionnaire. The collected data were analyzed qualitatively and quantitatively. This ethnomedicinal knowledge was compared against the available scientific literature for reports of related uses and studies of phytochemical compounds responsible for respective ailments. Results: A total of 84 species of plants, mostly herbs, belonging to 42 families were identified for the treatment of 70 types of ailments. These ailments were categorized into 16 categories. Leaves were the most frequently used plant parts and juice is the mode of preparation of major portions of the plant species. The most common mode of administration was oral ingestion and topical application. Informant consensus factor (Fic) values of the present study reflected the high agreement in the use of plants in the treatment of digestive system and respiratory system disorders among the informants. Diseases of the digestive system had highest use-reports and 3 species of plants, namely Centella asiatica (L.) Urban. (dysentery), Justicia gendarussa L. (asthma) and Ocimum tenuiflorum L. (coughing) had the highest fidelity level (FL) of 100%. Clerodendrum viscosum Vent., Achyranthes aspera L and Justicia gendarussa L. showed the highest relative importance (RI) value of 1.86. According to use value (UV) the most important species were Ocimum tenuiflorum L. (2.24) and Achyranthes aspera L. (2.15). Conclusion: Priority should be given for further phytochemical investigation to plants that scored highest FL, Fic, UV or RI values, as such values could be considered as good indicator of prospective plants for discovering new drugs. Since knowledge regarding traditional medicine being vulnerable day by day so traditional medicine in school curricula should be incorporated so that younger people could appreciate its usefulness. Also counseling of THPs and gardening of medicinal plants should be taken into consideration immediately in order to smooth continuance and extension of traditional medical knowledge and practice for ensuring safe and effective therapy.

  Bandarban Hill Tracts, Bangladesh, Chemical constituents, Ethnopharmacological survey, Traditional health practitioners
  Thanchi Upazila (Bandarban district), Bangladesh
  00-01-2011
  00-12-2012
  Development of Host and Medicinal Plants
  Medicinal Plants

An ethnopharmacological survey of medicinal plants used by the traditional health practitioners (THPs) of Thanchi, a remote area of Bandarban Hill Tracts was conducted in order to conserve the information regarding traditional uses of medicinal plants and analyze the data with different qualitative and quantitative parameters to identify the important species used in traditional medicine.

2.1. Study area Thanchi Upazila (Bandarban district) with an area of 1020.82 km2 , is bounded by Ramu upazila on the north, Arakan (Myanmar) on the south, Chin (Myanmar) and Belaichhari upazila on the east, Alikadam and Lama upazilas on the west. The principal river is Sangu (Shankha). Total population is 16104 of which 22.36% is ethnic nationals (Marma, Murong, Tripura, Khumi, Boam, Chakma, Tonchangya, and Khyan) (Banglapedia: National encyclopedia of Bangladesh (2003)). Among them Marma was the most prominent one. They are relatively illiterate but possess vast knowledge in traditional medicine. On the other hand Chakma are relatively educated and hence tend to use modern medicine largely. These tribes are native to this area for so many years and possess more or less similar culture. This ethnomedicinal survey was conducted in Thanchi sadar, Tindu, Remecree, Choto madok and Boro madok in Thanchi Upazila, Bandarban. 2.2. Sampling of informants The ethnopharmacological survey was conducted during January 2011–December 2012. Six field visits consisting of 6 days per survey were conducted. Interviewees were local traditional health practitioners (THPs) with practical or empirical knowledge on medicinal plants. A total of 53 people mostly from predominant tribals such as Marma, Tonchangya, Chakma, Khumi and Tripura tribals were interviewed for this purpose. During the selection of informants, gender, age, educational background and experience on use of traditional medicinal plants were taken into consideration. 2.3. Ethnomedicinal data collection The objectives of the study were clearly explained and written consent was obtained by interviewers from each informant. The participating THPs were identified with the help of local people familiar with traditional healers and who could communicate with local communities. Each THP was interviewed alone to ensure confidentiality among them. However two group meetings were also organized participated by 15 THPs who had given consent to discuss about their practice. Open-ended and semi structured questionnaire (Cotton, 1996; Bruni et al., 1997) were used for the purpose. The record questionnaires used included two sections: Section 1 dealt with personal information including age, sex, educational background and experiences of the THPs related to medicinal plants and Section 2 was about their practice including the following information: (a) the local name of the plants (b) plants part/s used (c) the method of preparation (d) nature of plant material (e) relative abundance at the area (f) habitat of the plant species (g) mode of application (h) medicinal uses of particular plant. Interviews were conducted using the Bengali language. Informants were asked to collect the plants they used for the treatment of various ailments. These specimens were pressed, preserved and later identified by identified by one of the authors (the Botanist M.M.K. Mia, Principal Scientific Officer and Consultant of Bangladesh National Herbarium, Dhaka). The voucher specimens of each plant were deposited in the Bangladesh National Herbarium. Research articles, books and relevant web pages were also studied with the aim to accumulate data of phytochemical compounds as well as any known toxicity present in the plants. The compounds that were frequently found in the reported plant species were also documented. 2.4. Data analysis The species were listed in alphabetical order by scientific name, family, local name, general name, plants part/s used, mode of preparation, mode of application, habit, habitat, relative abundance, conservation status, nature, solvent used and frequency of citation (FC). The FC of the species of plants being utilized was evaluated using the formula: FC¼(Number of times a particular species was mentioned/Total number of times that all species were mentioned) 100 Frequency distribution was calculated by using the IBM SPSS Statistics.

  Journal of Ethnopharmacology (2014),
  http://dx.doi.org/10.1016/j.jep.2014.05.043i
Funding Source:
1.   Budget:  
  

Modern health care facilities in Thanchi are still not adequate and the economic condition of the indigenous people are not good enough, so that they are largely dependent on the empirical knowledge of the THPs for the management of their health problems. The traditional medicine used in this remote area Very often lacks phyto-therapeutic evidence. And hence it is necessary to perform phytochemical or pharmacological studies to explore the potential of plants used for medicinal purposes. Furthermore, rapid decrease of senior inhabitants will straightly lead to more losses of this crucial traditional knowledge as they are transmitted only verbally due to lack of proper documentation. Hence, this study represents a useful and long-lasting documentation of the medicinal plants of the area, which can contribute to preserve knowledge on the use of medicinal plants in this region and also stimulate the interest of future generations on traditional healing practices. However, measures should be taken to train up the THPs regarding the harmful effects of irrational uses of plants in order to ensure safe therapy as well as it would be important to provide them some contemporary information at the level of their comprehension and practices. In this way we can carry out necessary steps for not only further investigation of important plant species of the study area but also to protect the vulnerable plant species from being endangered.

  Journal
  


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