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Research Detail

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A. Hossain
Department of Biochemistry and Molecular Biology, Hajee Mohammad Danesh Science and Technology University, Dinajpur 5200, Bangladesh

M. A. Sayed*
Department of Biochemistry and Molecular Biology, Hajee Mohammad Danesh Science and Technology University, Dinajpur 5200, Bangladesh

B. C. Sarker
Department of Agricultural Chemistry, Hajee Mohammad Danesh Science and Technology University

U. K. Majumder
Department of Statistics, Hajee Mohammad Danesh Science and Technology University, Dinajpur-5200, Bangladesh

M. A. Hossain
Department of Biochemistry and Molecular Biology, Bangladesh Agricultural University, Mymensingh 2202, Bangladesh

A cross-sectional survey was conducted in Dinajpur district, Northwest Bangladesh, in order to determine the risk factors associated with the development of diabetes from pre-diabetes condition. Among the various possible risk factors, hypertension status, level of walk, dietary and smoking behaviour were selected as significant risk factors associated with the development of diabetes from the pre-diabetes condition. Pre-diabetes subjects with hypertension were 1.54 fold more possibility of diabetes than those of no hypertension. Developing diabetes were tended 2.10 and 1.64 fold among the people practicing one or two days walking and four to five days walking per week, respectively, in compare to the subjects having regular walking habit. Taking up sweet taste diet during pre-diabetes condition was also marked as risk factor which pushed the patients toward the development of diabetes in 2.12 times higher than the people who did not take sweet taste diet during pre-diabetes condition. Smoking behaviour of the pre-diabetes patients was also identified as a significant risk factor of diabetes. The study indicated that the ex-smokers and current smokers were 1.53 times and 1.73 times, respectively, more possibility of migrating from pre-diabetes condition to diabetes one in compare to those who never took smoke. However, for checking the development of diabetes from pre-diabetes condition and establishing proper strategy as well, a deep and large scale research is highly recommended with these identified risk factors. 

  Diabetes, Hypertension, Prevalence, Risk factor
  Dinajpur district, Northwest Bangladesh
  00-01-2011
  00-06-2011
  Socio-economic and Policy
  Health hazard, Risk

Quantifying the prevalence of diabetes and identifying the individuals affected by diabetes, now and in the future, are important to allow rational planning and allocation of resources for diabetic prevention and control. In addition, the identification of risk factors for diabetes would allow better identification of people at risk for diabetes and more effective, efficient application of preventive measures. Therefore, the purpose of this study was to estimate the prevalence of socioeconomic, demographic and heath attributes of diabetes people as well to identify the risk factors for diabetes people from pre-diabetes condition in Dinajpur District of Bangladesh.

Study location: A cross-sectional survey was conducted in Dinajpur district of Northwest Bangladesh, named Dinajpur. Study was conducted on 359 diabetes people of study area with different age and sex groups. Objective oriented data was collected from January to June 2011 from diabetes and pre-diabetes patients who came to the hospital for getting service in Dinajpur Diabetes and Swastha Seba Hospital, Bangladesh.. The ethical clearance and approval were respected in the surveys. The protocol was approved by the Dinajpur Diabetes and Swastha Seba Hospital, Bangladesh.

Survey and sampling: During survey, there are 359 people of different ages and sex groups who are from different locations of Dinajpur District. Respondents were chosen who were more than 16 years old and who were able to understand clearly the instructions of the survey. All the subjects had answered voluntarily and confidently against the administered pre-tested questionnaires. All individuals were given an identification number. For study we were selected 359 out of 12,000 diabetes and pre-diabetes patients by systematic random sampling during. Pregnant women and disabled persons, who were unable to face simple questions, were avoided from the study. Initial contact was made with individuals and their families to provide information to them about the study and to obtain informed consent. Data relating to their socioeconomic, demographics and health status collected during interview and clinical examinations were performed at Dinajpur Diabetic and Swastha Seba Hospital. Each participant's was interviewed for the status of physical activities, family history of diabetes, hypertension, annual income etc. By following with proper aseptic precautions, 5 ml. of venous random blood was taken for blood glucose estimation. Fasting blood glucose was estimated by the glucose-oxidase method using the auto analyzer. After estimation of random blood sugar (RBS), the participants were classified into normal, impaired glucose tolerance (IGT) and diabetes based on the diagnostic criteria of WHO and American Diabetes Association (<7.8 mmol/l = normal, 7.8-11.0 mmol/l = IGT, >11.1 mmol/l = DM).

Anthropometrical and Blood Pressure Measurement: Anthropometrical measurement indicated height, weight and Body Mass Index (BMI) of patients. Height was measured by using stadiometer, interviewed standing upright on a flat surface without shoes and body weight was taken to the nearest 0.1 kg by a digital bathroom scale with light clothes. BMI was calculated as a ratio of weight in kg divided by height in meters squared. Blood pressure level was recorded in the procedure described by Akhter et al. (2011). 

Statistical Analysis: Descriptive statistics on the prevalence of diabetes was computed. Diabetes prevalence at different levels of categorical independent variables (e.g., age, sex and locations) were calculated. Multiple logistic regressions was applied to identify diabetes risk factors, and to compare their relative importance. Statistical significance was set at α = 0.05 (P-value < 0.05), in some cases α = 0.10 was considered. Statistical software SPSS (Ver. 16.0) was used for all statistical calculations. 

  Journal of Science and Technology 11(June 2013): 80-85
  
Funding Source:
1.   Budget:  
  

It concluded that hypertension, level of work, dietary behavior, and smoking behavior were marked as contributing risk factors associated with the development of diabetes from pre-diabetes conditions in the Dinajpur district of Bangladesh. For developing a proper strategy to control diabetes, further large-scale but intensive studies are highly deserved.

  Journal
  


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