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Control of Infectious Bursal Disease in Bangladesh

M. K. Hossain
Dinajpur Govt. Veterinary College, Busherhat, Dinajpur, Bangladesh.

M. M. Amin
Dept. of Microbiology and Hygiene, Bangladesh Agricultural Univeristy, Mymensingh, Bangladesh.

M. S. R. Khan
Dept. of Microbiology and Hygiene, Bangladesh Agricultural Univeristy, Mymensingh, Bangladesh.

M. Ahmed
Dinajpur Govt. Veterinary College, Busherhat, Dinajpur, Bangladesh.

S. M. H. Rashid
Dinajpur Govt. Veterinary College, Busherhat, Dinajpur, Bangladesh.

Abstract/ Executive Summary:

The aim of the study is to take a step to control the infectious bursal disease (I BD) ill Bangladesh by preparing infectious bursal disease virus vaccine (IBDV)from the localfield IBD V isolates after identification of local field strains. For this one selected local field IBDV isolate, one commercially available live attenuated IBDV vaccine Bur-706 (RP) and one killed IBDV vaccine Gumboriffa (RP) were used ill this study. A total of 100 specific pathogen free (SPF) chicks (Starbrow) of 0,7,14,21 and 28 days age (taking 20 in each group) were used for study the serologic response with a selected local field IBDV isolate. Similary two other vaccines were vaccinated in each 100 (SPF) chicks of similar age groups. After collection of sera weekly for upto six weeks from all groups the sera were subjected to SNT, PHA test and AGPT against a specific IBDV antigen. Through this investigation it is found that the local field IBDV isolate demonstrate a better serologic response than that o] commercially available live or killed IBDV vaccines. So, it may be concluded that the commercially available imported vaccines can not induce sufficient immune response to protect the chickens in Bangladesh. It may be due to degradation of the vaccine quality ill a new environmental condition or due to antigenic dissimilarities among the local field virus and the imported vaccines. So it may be opined that, if a step is taken to control the infectious bursal disease (I BD) in Bangladesh by preparing infectious bursal diseases virus (IBDV) vaccine from the local field IBDV isolates after identification of local field strains, then it may be easy to control the IBD in Bangladesh.

Keywords: Shelter, Stocking density, Growth, Mastacembalus armatus

Location: Dept. of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh, Bangladesh.

Start Date:

End Date:

Program Area: Pest Management

Commodity: Diseases

Objectives:

To control the infectious bursal disease (IBD) in Bangladesh by preparing infectious bursal disease virus vaccine (IBDV) from the localfield IBD V isolates after identification of local field strains.

Methodology:

IBDV field isolates Naturally occurring IBDV isolates were isolated from the IBDV suspected sick and dead birds collected from some selected poultry farms in Mymensingh and Dhaka region of Bangladesh. As a source of virus the bursa and spleen were collected. The isolates were identified as IBDV after cultivation in embryonated chickenn eggs (ECE) and in chickens in the Microbiology Laboratory in the Department of Microbiology and Hygiene, B.A.U, Mymensingh. Later the isolates were confirmed through SNT with the specific antisera raised in SPF chickens.A total of 6 field isolates were subjected to chicken embryo mortality test. The death pattern were recorded and the isolate showing lowest embryo mortality was selected and used in this study. Commercially available live IBDV vaccine BUR-706 of Rhone-Poulenc and a killed IBDV vaccine Gumboiffa of the same pharmaceutical company were collected from the local market and were used in this study. Specific IBDV antigen was collected from the Dept. of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh, Bangladesh. The selected local field IBDV isolate was inoculated through intranasal route into the chicks of 0,7,14,21 and 28 days age group of birds at the dose rate of 100EID₅₀/ml. In each group 16 chicks were inoculated and 4 were kept as control. Commercial live IBDV vaccine BUR-706(RP) was vaccinated following the same procedure and schedule described in inoculation of selected local IBDV isolate. Commercial killed IBDV vaccine Gumboriffa (RP) was vaccinated subcutaneously at the dose rate 0.5 ml per chick following the schedule described in inoculation of selected local IBDV isolate. Sera from all group of birds were collected weekly for up to 6 weeks of inoculation and stored at-20°C.

Source of Information: Ban. J. An. Sc. 2003, 32 (1-2) : 65-70

Article Link (Online Journal):

Funding Source:

Total Budget (Tk.) :

Achievement/Findings:

It may be concluded that the commercially available imported vaccines can not induce sufficient immune response to protect the chickens in Bangladesh. It may be due to degradation of the vaccine quality ill a new environmental condition or due to antigenic dissimilarities among the local field virus and the imported vaccines. So it may be opined that, if a step is taken to control the infectious bursal disease (I BD) in Bangladesh by preparing infectious bursal diseases virus (IBDV) vaccine from the local field IBDV isolates after identification of local field strains, then it may be easy to control the IBD in Bangladesh.

Knowledge Management: Journal