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Intraluminal Pressures of Rumen and Lower Oesophageal Sphincter in Anaesthetized Sheep

M. A. Hossain
Department of Surgery and Obstetrics, Bangladesh Agricultural University, Mymensingh, Bangladesh.

Abstract/ Executive Summary:

A sphincter at the gastro-oesophageal junction in terms of high pressure zone was demonstrated In the anaesthetized sheep using both balloon and open tip catheters. The length of this lower oesophageal sphincter (LOS) wes measured to be 2.9 cm. The resting LOS pressure using balloon tip catheter was 25.6 mmHg and that using open tip catheter was 14.3 mmHg. This difference was highly significant. The rumen pressures were measured to be 10.01 and 13.6 mmHg with balloon tip and open tip catheters respectively. The LOS-rumen pressure gradient using balloon tip catheter was 16.6 mmHg and that using open tip catheter was 0.7 mmHg. This difference was again highly significant.

Keywords: Intraluminal pressures. Rumen, Lower oesophagaa I sphincter anaesthetized sheep.

Location: Department of Surgery and Obstetrics, Bangladesh Agricultural University, Mymensingh

Start Date:

End Date:

Program Area: Animal Health and Management

Commodity: Sheep

Objectives:

To demonstrate the presence of a HPZ at the gastro-oesophageal junction, its length and the resting intraluminal pressures.

Methodology:

Eleven Blackface sheep were used in this investigation. The body weights of these sheep ranged from 35-45 kg. Management of the animals was performed in a similar way as described elsewhere (Hossain. 1987). Anaesthesia: Induction of anaesthesia was performed with a mixture of halothane (4%). nitrous oxide and oxygen 50:50) using a face mask and a Magill system. After induction. anaesthesia was maintained following the technique of Hossain and Camburn (1983). The animals used in this study were not starved and were positioned in right lateral recumbancy. the gastro-oesophsgeal junction, any change in baseline pressure was monitored. The existence of the LOS Was detected by the appearance of a HPZ and the length of the sphincter was delineated by that portion of the with- drawal tracing that indicated pressure greater than those obtained in The rumen. After the recognition of a LOS at the gastro-oesophageal junction, the intraluminal pressures were recorded by 'stationarry technique', In this technique, the recording tip was continuously maintained in the LOS and any displacement of the cathter was restored by moving the catheter up or down. The cranial displacement of the catheter was recognized by the appearance of negative intra-thoracic pressure and was characterized by the downward deflection of the respiratory pressure changes. The caudal displacement of the catheter was identified by the presence of characteristic ruminal pressure changes with a stable resting baseline, The LOS pressure changes were characterized by its rapidly fluctuating baseline pressure. The patency of the catheter was occasionally impaired (evident from the absence of respiratory prespure changes reduction of baseline pressure) and was restored by flushing the catheter with a few milliliters of water. Once the positioning of the recording tip in the LOS was achieved, the pressures were monitored over a period of 60 minutes.

Source of Information: Bangladesh J. Agril. Sci. 17(1): 133-139: January. 1990

Article Link (Online Journal):

Funding Source:

Total Budget (Tk.) :

Achievement/Findings:

The length of LOS was found to be 2.9 ±0.3 cm. The length of LOS in the anaesthetized sheep using a 1.0 cm long balloon No single factor appears to be responsible for maintaining LOS tone, but probably it involves a number of coordinated factors which may include (i) a tonic excitatory nerve activity of either extrinsic or intrinsic origin, (ii) circulating gastro-intesiinal hormone, (iii) a local hormone, (iv) inherent properties of the smooth muscle cell. (v) a combination of two or more of the above factors.

Knowledge Management: Journal