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Immune Response Capability of `shuvra’ Chicken

M. S. Sabrin
Department of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh

S. Saha
Department of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh

M. M. Amin
Department of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh

Abstract/ Executive Summary:

The study was carried out to determine the humoral immune response to Newcastle Disease Virus (NDV) and Bangladesh Agricultural University Fowl cholera (BAUFC) vaccines in Shuvra chicken, a newly develop chicken strain by BLRI (Bangladesh Livestock Research Institute). Ten Shuvra chickens were vaccinated with Baby Chick Ranikhet Disease Vaccine (BCRDV) at day 7 through intra ocular route (i/o) and with Ranikhet Disease Vaccine (RDV) at day 35 through intramuscular (i/m) route. Vaccine induced serum Haemagglunination Inhibition (HI) antibodies were measured by HI test. Two weeks after final immunization all vaccinated and control Shuvra chickens were challenged with virulent field isolates of NDV where all the vaccinated birds survived without showing any typical signs of NDV during the period of ten days observation period and all the control chickens died. Another 10 Shuvra were vaccinated twice with BAUFC vaccine through intramuscular route at day 42 and 70, and 10 Shuvra chickens were kept as unvaccinated control. This vaccine also induced significantly higher level of antibody titre as determined by Passive Haemagglutination (PHA) test. Vaccinated chickens showed significantly higher survival (80%) following challenge with virulent fowl cholera isolate and all the control birds died within 10 days of observation period.

Keywords: Shuvra, Chick, Vaccine, Antibody titre, Fowl cholera

Location: Mymensingh.

Start Date:

End Date:

Program Area: Animal Health and Management

Commodity: Chicken

Objectives:

to investigate the immune response capability of this strain of birds with Newcastle disease vaccines and Fowl cholera vaccines.

Methodology:

Baby Chick Ranikhet Disease Vaccine (BCRDV) and Ranikhet Disease Vaccine (RDV) were obtained from Livestock Research Institute (LRI), Mohakhali, Dhaka. Virulent field isolate of Ranikhet/Newcastle Disease Virus (NDV) used for challenge was obtained from the repository of the Department of Microbiology and Hygiene, BAU, Mymensingh. FC vaccine called BAU Fowl cholera vaccine was collected from LPVRPC, and used according to the instruction provided by manufacturer. Virulent field isolate of Fowl cholera causing bacteria used for challenge was obtained from the repository of the Department of Microbiology and Hygiene, BAU, Mymensingh.A total of 40 day-old Shuvra chicks were obtained with the courtesy from BLRI, Savar, Dhaka. The chicks were then reared in the experimental poultry shed and were provided with sufficient nutritional diet and other management requirements with proper biosecurity.Sixteen days after secondary vaccination with RDV, the chickens of group A and B were challenged with virulent field isolate of NDV intra-nasally (i/n) 0.1mL per bird containing 2ELD50 dose, which corresponded to about 100% mortality in chickens of 10-weeks of age (Sarkar et al., 2012).Student’s t-test was performed to determine significant differences in HI and PHA titres. Protection tests were analyzed by Mantel-Cox log rank test. A P value at ≤ 0.05 was considered statistically significant.

Source of Information: Bangl. J. Vet. Med. (2012). 10 (1&2): 1-7

Article Link (Online Journal):

Funding Source:

Total Budget (Tk.) :

Achievement/Findings:

From this investigation, it may be concluded that- (i) Almost high level of antibody titre was observed in Shuvra following vaccination with either NDV or BAU fowl cholera vaccine. (ii) Shuvra were able to survive about 90% in a very hot, humid, congested and crowded environment following challenge.

Knowledge Management: Journal