A research work was conducted both in the field and lysimeter at the Bangladesh Institute of Nuclear Agriculture farm, Mymensingh during November 1998 to March 1999 to study the water balance components and crop coefficients of wheat in silty loam soil. The bulk density of the experimental soil was found to be 1.42 and 1.00 gm/cc in field and lysimeter, respectively. The volumetric field capacity and hydraulic conductivity of the field and lysimeter soil were 44%, 0.12 cm/day and 49.040%, 0.24 cm/day, respectively. There were five treatments, each replicated four times in a randomized block design in the field and had no replication in the lysimeter. The various components of water balance viz. irrigation, effective rainfall, change in soil moisture storage, deep percolation, flux density, actual evapotranspiration were determined. Besides those, crop coefficients al different growth stages, total water requirement, water use efficiency and harvest index were also determined. Total change in soil moisture storage (depletion) under different treatments were 10.755, 10.575, 10.785, 12.300 and 14.904 cm in the field; and 19.145, 15.400, 13.860, 17.039 and 19.140 cm in the lysimeter, respectively. Total change in soil moisture was more in the lysimeter than in the field. Zero flux plane was found to very near to the soil surface in the early stage of the crop growth. With the span of time, zero flux plane gradually moved downward and upward soil water flux increased from the deeper layer of the soil profile. Total deep percolation for different treatments were 3.91, 3.95, 4.09, 1.11 and 1.31 cm, respectively. There was no deep percolation in the lysimeter. Total water requirement of wheat under different treatments were 14.405, 13.675,22.515, 22.147 and 20.356 cm in the field and 19.145, 17.269, 16.590, 20.809 and 21.350 cm in the lysimeter, respectively. Actual evapotranspiration was maximum during yield formation stage (16.597 em) in the field and during vegetative stage (10.360 crn) in the lysimeter, respectively. Crop coefficient values varied under irrigated and non-irrigated conditions. Under the irrigated condition, crop coefficient values were 0.40, 0.65, 1.79, 0.35 and 0.68, 0.89, 0.89, 0.30 at the early, vegetative, yield formation, ripening stages in the field and lysimeter, respectively. Highest water use efficiency was observed at early stage, both in the field and lysimeter, respectively.