Materials and Methods Collection and preparation of test materials: M. pruriens was collected from the University of Rajshahi Campus and identified by the Department of Botany, University of Rajshahi, where a voucher specimen is kept in the herbarium. The plants were chopped into small pieces, dried under shade and powdered using a hand grinder, weighed and placed in separate conical flasks to add Pet. ether, CHCl3 and MeOH (Merck, Germany) (100gm × 300ml × 2times) for 48h. Filtration was done by Whatman filter paper (made in USA) at the 24h interval in the respective flasks followed by evaporation until the extracts were left. The extracts were then removed to glass vials and preserved in a refrigerator at 40C with proper labeling. Collection and culture of test insect: Adults of T. castaneum were reared in glass beakers (500ml) in a standard mixture of whole-wheat flour with powdered dry yeast (19:1) in an incubator at 30 ±0.5°C without light and humidity control for a continuous supply of adults during experimentation. Dose-mortality test: The dose-mortality responses of M. Pruriens were observed by surface film method. The concentrations used were 2.038, 1.529, 1.019, 0.510 and 0.254mg cm-2 for Pet. ether extract of fruit followed by 2.548, 2.038, 1.529, 1.019, 0.510 and 0.254mg cm-2 and 3.567, 3.057, 2.548, 2.038, 1.529, and 1.019mg cm-2 for CHCl3 and CH3OH extracts; 4.080, 3.567, 3.057, 2.548, and 2.038mg cm2 for Pet. ether extracts of aerial part as well as 2.548, 2.038, 1.529, 1.019, 0.510 and 0.250mg cm-2 ; and 2.548, 2.038, 1.529, 1.019, 0.510 and 0.254mg cm-2 for Pet. ether and CH3OH extracts of root against T. castaneum in the dose mortality experiments. Each of the doses were diluted in 1ml of solvent, poured into Petri dishes and allowed to dry out. Ten adult beetles were released in each Petri dish, and the experiment of all the doses for each of the extracts were replicated in a thrice. The mortality was assessed for 12h, 24h, 36h, and 48h of exposure. Statistical Analysis: The mortality (%) was corrected using Abbott’s formula: Pr = Po − Pc /100 – Pc×100 Where, Pr = Corrected mortality (%), Po = Observed mortality (%), Pc = Control mortality (%). The data were then subjected to probit analysis according to Finney [16] and Busvine [17] using a software developed at the University of Newcastle upon Tyne, UK. Repellent Activity: The repellent activity test was adopted from the method (No. 3) of McDonald et al. with some modifications. Half filter paper discs (Whatman No. 40, 9cm diam.) were treated with the selected doses of 0.629, 0.314, 0.157, 0.0786, 0.0393mg cm-2 for all extracts and were then attached lengthwise, edge-to-edge, to a control half-disc with adhesive tape and placed in the Petri dishes. The orientation was changed in the two remaining replicates to avoid the effects of any external directional stimulus affecting the distribution of the test insects. Ten adult insects were released in the middle of each of the filter paper circles. Each concentration against of the solvents was tested for five times. Insects that settled on each of the non-treated half of the filter paper discs were counted after 1h and then observed repeatedly at hourly intervals for five hours. The average of the counts was converted to percent repulsion (PR) using the formula of Talukder and Howse: PR = (Nc – 5) × 20, where, Nc is the percentage of insects on the untreated half of the disc. Brine shrimp nauplii lethality test: Brine shrimp cycts were purchased from Kalabagan, Dhaka and kept in aerated seawater at room (25-30°C) temperature and took 30-48h to give nauplii. The series of concentration were for Pet. ether extracts of the fruit were: 400, 200, 100, 50 and 25ppm; followed by 100, 50, 25, 12.5 and 6.3ppm; and 100, 50, 25, 12.5 and 6.3ppm for CH3OH and CHCl3 extracts as well as 800,400, 200,100 and 50ppm; 400,100 and 25ppm; and 200, 100, 50, 25 and 12.5ppm for Pet. ether, CHCl3 and CH3OH extracts of aerial parts and for Pet. ether extracts of root were 50, 25, 12.5 and 6.3ppm; followed by 200, 100 and 50ppm; and 50, 25 and 12.5ppm for CHCl3 and CH3OH extracts were selected respectively. Ten freshly hatched nauplii were added to each of the test tubes with different concentrations mentioned earlier and observed mortality after 6, 12, 18, 24 and 30h of exposures. The data were then subjected to probit analysis.