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Appraisals of Bangladeshi Medicinal Plants Used by Folk Medicine Practitioners in the Prevention and Management of Malignant Neoplastic Diseases

Md. Nur Kabidul Azam
Ethnobotany & Ethnomedicine Division, TechB Herbal Solution, Kushtia 7040, Bangladesh

Md. Mizanur Rahman
Ethnobotany & Ethnomedicine Division, TechB Herbal Solution, Kushtia 7040, Bangladesh

Samanta Biswas,2 and
Medical College for Women & Hospital (MCW&H), Uttara Model Town, Dhaka 1230, Bangladesh

Md. Nasir Ahmed
Ethnobotany & Ethnomedicine Division, TechB Herbal Solution, Kushtia 7040, Bangladesh

Abstract/ Executive Summary:

Cancer is a group of diseases which is categorized to differentiate into diverse cell types and move around in the body to sites of organogenesis that is key to the process of tumor genesis. All types of cancer fall into the group of malignant neoplastic diseases. In Bangladesh, cancer is now one of the foremost killer diseases and its personal, social, and economic bearing are huge. Plantderived natural compounds (vincristine, vinblastine, etoposide, paclitaxel, camptothecin, topotecan, and irinotecan) are useful for the treatment of cancer. Since there is no extensive ethnobotanical research study in Bangladesh regarding the traditional uses of medicinal plants against neoplasms, therefore, a randomized ethnopharmacological surveys were carried out in 3 districts of Bangladesh to learn more about the usage of anticancer medicinal plants and their chemical constituents having antineoplastic activity. Comprehensive interviews were conducted to the folk medicine practitioners and medicinal plants as pointed out by them were photographed, collected, deposited, and identified at the Bangladesh National Herbarium. The various plant parts have been used by the healers which included whole plant, leaves, fruits, barks, roots, and seeds. This study evaluated considerable potential for discovery of novel compounds with less side effects in the management and prevention of malignancy in cancer.

Keywords: Bangladeshi, Medicinal Plants, Malignant Neoplastic Diseases

Location: Three districts of Bangladesh, namely, Jessore, Khulna, and Narail

Start Date: 00-10-2013

End Date: 00-03-2014

Program Area: Development of Host and Medicinal Plants

Commodity: Medicinal Plants

Objectives:

It was objective of the present study to conduct a randomized ethnopharmacological survey to learn more about the medicinal plants used by folk medicine practitioners of Bangladesh for the treatment of cancer and also to do comprehensive study on several published articles attributed to the in vivo orin vitro anticancer properties of these species.

Methodology:

2.1. Geographical Location of the Survey Area. The present randomized surveys were carried out between October 2013 and March 2014, among the Kabirajes of three districts of Bangladesh, namely, Jessore, Khulna, and Narail. Jessore district geographically is in the southwestern region of Bangladesh. It is located at 23⁰ 10' 0" North, 89⁰ 13' 0" East, bordered by Khulna and Satkhira district to the south, India to the west, Magura and Narail district to the east, and Jhenaidah district to the north. Khulna and Narail district. These three districts are a part of Khulna division. The surveys were conducted with the help of a semistructured questionnaire and the guided field-walk method. A total of 5 Kabirajes (36–60 years) were interviewed during the surveys. Kabirajes were asked whether they know about cancer and whether they treat the cancer on a regular basis. Kabirajes were selected based on their confirmatory answer to both questions. The Kabirajes mentioned the plants with which they treated cancer and took the interviewers to spots from where they collected the plants. All interviews were conducted in the Bangla language. The plants were shown along with providing of local names and the parts used. Plant specimens were collected and dried in the field and later brought back to Dhaka for complete identification at the Bangladesh National Herbarium. Nomenclature of the identified species was documented from the plant list database [http://www.theplantlist.org/].

Source of Information: International Scholarly Research Notices Volume 2016, Article ID 7832120, 12 pages

Article Link (Online Journal): http://dx.doi.org/10.1155/2016/7832120

Funding Source:

Budget:

Total Budget (Tk.) :

Achievement/Findings:

Among twenty plant species, four of the species used by folk medicine practitioners have no strong published data regarding anticancer or cytotoxic activities. These 4 species are C. inerme, M. paniculata, S. sesban, andV. officinalis. From just a brief survey of the literature, it appears that the rest of the sixteen plants used by the Kabirajes in three districts of Bangladesh present considerable potential in the treatment of cancer. Further scientific studies need to be conducted on these plants towards discovery of lead compounds, which can lead to formulation of new drugs for the prevention and management of malignant neoplastic diseases with giving less or no side effects.

Knowledge Management: Journal