Analytical grade instruments and reagents that were used for dissolution studies of Standard Paracetamol sample (99.8% potency) were collected from Incepta Pharmaceuticals Ltd, Dhaka. 2.1. Apparatuses A Dual beam Shimadzu UV-visible spectrometer (UV mini-1700, Shimadzu Corporation, Kyoto, Japan with 1 cm quartz cells). HANNA HI 2211 pH meter (Romania), automatic tablet dissolution tester with eight-basket system UDA-80 USP Standard (Veego, India). 2.2. Samples Collection Randomly selected Top eight Paracetamol tablets (manufacturing date was not more than three month ago from the period of procurement) from various drug stores. Manufacturing license number, group number, and time of production and expiry times before procuring were properly checked. Their proper codes were also obtained, such as P01, P02, P03, P04, P05, P06, P07 and P08. The considered active components of paracetamol were 500 mg and they were packed in groups or in blister packing. The strip or blister packs stored at 25±2°C for four weeks before the dissolution study in order to evaluate any organoleptic changes. 2.3. The Formulation of the Selected Sample The claimed average formulary ingredients of the selected paracetamol 08 tablets are listed below: Paracetamol BP or USP (500.00±3.0 mg), Maize Starch BP (70.50±0.18 mg), Poly vinyl pyrrolidone BP (3.00±0.80 mg), Methyl paraben sodium BP (0.50±0.07 mg), Propyl paraben sodium BP (0.05±0.02mg) Sodium starch glycolate BP (5.5±0.25 mg), Magnesium stearate BP or USP (2.00±0.15 mg), Purified Talc BP or Pharma grade (5.00±03 mg). The claimed average of coating material of the 08 paracetamol tablets are mentioned below: Hydroxy propyl methyl cellulose (HPMC) BP or USP (4.00±0.30 mg), Titanium dioxide BP (1.00±0.40 mg), Purified Talc BP (1.50±0.50 mg), Isopropyl alcohol BP or Ph. Grade (60.00±2.5 mg), Methylene chloride BP or Ph. Grade (70.00±0.25 mg), PEG-6000 BP (1.00±0.30 mg). The claimed dissolution (% Drug) of the 08 paracetamol tablets as below: After 10 min: P01 (70.78%), P02 (70.50%, P03 (68.00 %), P04 (72.50 %), P05 (75.00%), P06 (77.00 %), P07 (73.50%) and P08 (85.00 %). After 20 min: P01 (75.63%), P02 (81.73%), P03 (77.26 %), P04 (88.29 %), P05 (88.35%), P06 (83.64 %), P07 (89.33%) and P08 (90.23 %). After 30 min: P01 (85.28%), P02 (88.17%), P03 (93.23%), P04 (95.49 %), P05 (94.25%), P06 (92.42 %), P07 (95.38%) and P08 (94.00 %). 2.4. Standard Solution Preparation 100 mg Paracetamol powder (99.8% pure) was taken in a 100 ml volumetric flask and added with 10 ml of 0.1N NaOH. 2.5. In Vitro Dissolution Study The apparatus was maintained at 37±0.5°C with a grade of agitation of 50 revolutions/minute and 900 ml of dissolution medium per vessel was applied. The experimentation was conducted in two stages. Firstly, apply the 500 mg Paracetamol tablet employing buffer dissolute on the medium. Secondly, 700 ml of buffer and 200 ml of freshly prepared mango juice pulp were added for the dissolution study. For the performance of in vitro dissolution examination, a simulated gastric medium (pH 1.2) is mandatory. 2.6. Preparation of Simulated Gastrointestinal Condition To prepare the Chloride Buffer pH 2.0 (0.1 N HCl; pH 2.0), dissolve 6.57g KCl in water, add 119 ml of 0.1N HCl and dilute to 1000ml water for the simulated gastrointestinal condition. Presentation of mathematical models for drug release.