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In Vivo Pharmacological Activities of Medicinal Plants of Khalishpur Upazila, Khulna District, Bangladesh: a Mini Review

Imran Mahmud
Pharmacy Discipline, Life Science School, Khulna University, Khulna 9208, Bangladesh

Sanjib Saha*
Pharmacy Discipline, Life Science School, Khulna University, Khulna 9208, Bangladesh

Md. Khirul Islam
Pharmacy Discipline, Life Science School, Khulna University, Khulna 9208, Bangladesh

Faroque Hossain
Pharmacy Discipline, Life Science School, Khulna University, Khulna 9208, Bangladesh

Abstract/ Executive Summary:

Since primitive time, human has always attempted to mitigate suffering and diseases by using natural flora. Medicinal plants are being used to treat various ailments as well providing new leads to discover new potential drugs. Moreover, two-third of our commercial drugs is of natural origin. Their traditional uses have attracted the attention of researchers, and as a result, reports on biological activity studies of medicinal plants are increasing day by day. This review has been designed to compile and appraise the reports on antinociceptive, anti-inflammatory, antipyretic, and anti-diabetic activities of medicinal plants of Khalishpur Upazila, Khulna District, Bangladesh. In order to gather web-based information, Google Scholar, PubMed, Scopus, Scirus, and other pertinent literature were utilized. To report such activities, a total number of 32 reports on 27 plant species have been found so far.

Keywords: Khalishpur; Khulna; Antinociceptive; Anti-inflammatory; Antipyretic; Antidiabetic

Location: Khalishpur Upazila, Khulna District, Bangladesh

Start Date:

End Date:

Program Area: Development of Host and Medicinal Plants

Commodity: Medicinal Plants

Objectives:

This review aims to appraise these selective pharmacological activities of the plants of the study area so that advanced studies can be designed to identify new lead compounds as well as molecular basis of bioactivity.

Methodology:

Study Area Khalishpur is an Upazila of Khulna District in the Division of Khulna, Bangladesh. It is located at 22.8500°N 89.5361°E and total area is 11.47 km². Though this area possesses rich plant diversity only few plants have been screened for their pharmacological activities. That is why this area was selected to appraise some selective bioactivity studies so far conducted on locally available medicinal plants.

Google Scholar, PubMed, Scopus, and Scirus were used to search published literature since 1950. Other additional publications, namely, books and journal articles, were also investigated. Locally available medicinal plants of the study area were searched for bioactivities. This table represents a general outline of the published works that have been done so far on locally available medicinal plants for antinociceptive, anti-inflammatory, antipyretic and anti-diabetic activity. It also delineates the full botanical name of the plants species, plant parts used for the studies, screened activity, and the screening method with test animals.

Source of Information: PharmacologyOnLine; Newsletter • 2013 • vol.1 • 30 - 35

Article Link (Online Journal):

Funding Source:

Budget:

Total Budget (Tk.) :

Achievement/Findings:

This review has revealed that only a few studies have been done so far on the medicinal plants of Khalishpur Upazila. There is no report on bioactive compound isolation and identification of the mechanism of action. So, advanced studies like LC-MS, GCMS are required for identifying new lead compounds.

Knowledge Management: Newsletter